Search Results for: Selecting the Right Delivery System
Articles
Mustang Bio Presents Clinical & Preclinical Data on MB-101 for Treatment of Glioblastoma November 29, 2016
Mustang Bio, Inc., a Fortress Biotech company, recently announced that Phase I clinical data and preclinical data on its MB-101...EXECUTIVE INTERVIEW - PYRAMID: Prescription for Building Success Through Partnerships October 3, 2016
Medhat Gorgy, President and CEO of PYRAMID Laboratories, Inc., discusses his success in building futures with his clients and more importantly, the lessons he’s learned along the way.
COMPUTATIONAL METHODS - Formulation Development: An Innovative, Simulation-Based Approach August 30, 2016
Tom Reynolds, PhD, Matt Wessel, PhD, Sanjay Konagurthu, PhD, and Marshall Crew, PhD, report that computational methods, such as QM and MD simulations, are playing an ever-expanding role in drug discovery and development, and transforming advances in drug development at all stages.
DRUG DEVELOPMENT EXECUTIVE - Crown Bioscience: Enhancing the Drug Development Process May 31, 2016
Jean Pierre Wery, President of Crown Bioscience, discusses the requirement for more accurate research models in oncology research, focusing on PDX models that have the ability to more adequately represent the conditions and mechanisms of immunotherapy in human patients.
COMBINATION CORNER - How to Approach OTS Devices for Your Combination Product May 3, 2016
Lilli Zakarija, MSME, MBA, cautions that while OTS devices are already “developed” and on the market, they should still go through the device development design control process from the perspective of the combination product, and then let the design control process determine if the device meets the specific requirements of the CP.
SPECIAL FEATURE - Excipients: Enhancing the New, Poorly Soluble APIs June 1, 2015
Contributor Cindy H. Dubin interviews several excipient manufacturers who share their insights about the role excipients play in formulating and manufacturing drugs for improved bioavailability, solubility, and delivery.
CMOCRO: Intuitive Platform Provides Quick Access to Global Database of Pharmaceutical Suppliers, Supports Partnering Decisions April 30, 2015
By: Ashish Shukla, PhD CMOCRO is an intuitive platform designed to quickly access a global database of pharmaceutical...SPECIAL FEATURE - Outsourcing Formulation & Manufacturing Development: Using Data & Unique Approaches to Solve Solubility Issues, Target Profiles & Customize Products March 31, 2015
Contributor Cindy H. Dubin finds that CMOs are embracing development projects in an effort to establish longer-lasting partnerships with their pharma and biotech clients. These contract developers are deploying innovative techniques aimed at improving solubility and fast-tracking products to market.
SPECIAL FEATURE - Bioavailability & Solubility: A Demand for Enhanced Technologies & Materials is Spurring Innovation March 3, 2015
Contributor Cindy H. Dubin spoke with several contract research/manufacturing organizations on how they are successfully overcoming solubility/bioavailability challenges, such as matching APIs to formulations and choosing the best excipients.
EXECUTIVE INTERVIEW - 4P Therapeutics: Developing New & Innovative Transdermal Products June 3, 2014
Drug Development Executive: Steven Damon, Founder of 4P Therapeutics, discusses his vision for the company and how 4P intends to create new and innovative transdermal products that meet the needs of patients, physicians, and payers.
SPECIAL FEATURE - Outsourcing Formulation Development & Manufacturing: Early-Stage Partnerships Are On The Rise April 2, 2014
Contributor Cindy H. Dubin asked leading CMOs and CDMOs to describe the value-added services they offer with respect to formulation and manufacturing. Solving challenges of insufficient solubility, poor stability, identifying excipient candidates, and particle design topped their list of offerings.
DISPOSABLE TECHNOLOGY - Use of Disposable Technology in Clinical Fill & Finish Manufacturing: Benefits & Considerations March 31, 2014
Claudia Roth, PhD, reviews not only the benefits of using disposables, but the real-world variables to consider when converting to single-use technology. The pathway begins with the question, why use disposables?
BIOAVAILABILITY ENHANCEMENT - Navigating a Broad Spectrum of Solubilization Technologies: Part I of III September 5, 2013
In the past two columns, The Second Quadrant focused on excipients and the roles they play in the quest to...8/1/2012 July 30, 2012
BD Launches Thin-Wall Needle Technology BD Medical recently announced the launch of the BD Hyflow needle, a unique 27-gauge thin-wall...8/30/2011 August 25, 2011
Avantor Performance Materials Expands Portfolio Avantor Performance Materials recently announced it has expanded its portfolio by offering cGMP-manufactured Methylene Chloride...Unilife Commences Initial Supply of the Unifill Syringe to Sanofi July 25, 2011
Unilife Corporation recently announced it has commenced the initial supply of validated product of the Unifill syringe to Sanofi, as...7/26/2011 July 19, 2011
Daiichi Sankyo Launches Direct Oral Factor Xa Inhibitor Daiichi Sankyo Company, Limited recently announced the launch of LIXIANA (JAN: Edoxaban...
