Particle Sciences Acquires Exclusive License to Lyotropic Therapeutics' Delivery Technology
Particle Sciences, Inc. (PSI) and Lyotropics Therapeutics, Inc. recently announced PSI has acquired the exclusive rights to the Lyotropics’ LyoCell patent portfolio. The LyoCell technology allows for the solubilization, stabilization, and delivery of a wide range of compounds – both small and large molecule.
“LyoCells are proprietary lyotropic liquid crystal-based formulations that contain both polar and non-polar nano-domains,” said Robert Lee, PSI’s VP Pharmaceutical Development. “These unique structures create ideal conditions for the solubilization and stabilization of many pharmaceuticals and biopharmaceuticals. Made from GRAS ingredients, this technology is already in late-stage clinical development in an intravenous product and has applications in most routes of administration.”
Under the revenue-share agreement, PSI obtains a full license to the technology except for several compounds previously developed by LTI. It will offer the technology to its clients looking to increase bioavailability or develop parenteral formulations of difficult-to-solubilize compounds. Intellectual property around the stabilization of macromolecules is also included in the transaction.
“The LyoCell technology has proven to be highly effective in solving very difficult formulation problems and is the basis for several drugs now in or poised to enter the clinical stage,” added Vince Conklin, LTI’s CEO. “We are very pleased to have a partner like PSI, a leader in the formulation and drug delivery space, who is well positioned to further broaden exposure for the LyoCell technology and to employ its enormous utility.”
“The technology is protected by a family of very young patents offering protection to 2028 and beyond,” said Dr. Lee. “PSI is very excited to bring the technology to our clients as it addresses the top technical issues we face every day, namely solubility and bioavailability, while also providing solid patent protection. Lyotropic liquid crystals have proven to be an outstanding approach that utilizes GRAS ingredients, something very unusual today. We anticipate our clients using this for both new chemical entities as well as life-cycle extension efforts. In both situations, the LyoCell technology has a lot to offer.”
PSI is an integrated provider of drug development services focusing on emulsions, gels, micro- and nano-particulates, drug/device combination products, and highly potent compounds across all dosage forms. Through a full range of formulation, analytic, and manufacturing services, it provides pharmaceutical companies with a complete and seamless development solution that minimizes the time and risk between discovery and the clinic. For more information, visit www.particlesciences.com.
LTI, based in
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