September 2009

TABLE OF CONTENTS

Solid Lipid Nanoparticles for the Delivery of Pharmaceutical Actives
Andrew Loxley, PhD, believes SLNs offer a highly versatile platform and one that should be considered when working with APIs that present solubility and/or bioavailability challenges. 

A Hollow Microstructured Transdermal System (hMTS) for Needle-Free Delivery of Biopharmaceuticals

Kris Hansen, PhD; Scott Burton, PhD; and Mark Tomai, PhD; review how the hollow microstructured transdermal system penetrates the stratum corneum and provides fast, high-volume intradermal delivery of molecules traditionally restricted to syringe injection.

 

Enteric-Coated Aspirin Tablets: Disintegration Time

Antoine Al-Achi, PhD, and Divyesh D. Patel establish a disintegration profile for enteric-coated aspirin tablets as the US Pharmacopeia does not provide this information in its monograph pertaining to this dosage form.

 

Healthcare Reform & Needlestick Prevention Laws Inject Life Into Hand-Held Devices

Contributor Cindy H. Dubin talks with some of the industry’s leading developers and finds out that a push toward home-based healthcare as well as OSHA’s regulations governing needlesticks are creating a larger market than ever for safer and easier to use hand-held injection devices.

 

Colorcon: Continued Innovation in Formulation Partnersip

Drug Delivery Executive: Mr. James Coward, Colorcon’s Vice President, Corporate Development, discusses his company’s current business model, what makes them unique, and their approach to the future.

 

Gaining Access to Global & Specialized Services

Contributor Cindy H. Dubin asks some CMOs to describe how they are catering their services to better serve the Specialty Pharma audience. A greater emphasis on biotech manufacturing and access to worldwide expertise are among their offerings.

 

DEPARTMENTS

 

Market News & Trends

 

Excipient Update                                                                                        

Pharmaburst 500: Meeting the Challenge of ODT Formulations

 

Combination Update                                                                                  

FDA’s New Draft Guidance on Technical Considerations for Pen, Jet & Related Injectors Intended for Use With Drugs & Biological Products: Comments & Concerns

 

Technology Showcase

 

External Delivery

My Theory of Relativity: E=mc²

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