October 2010

TABLE OF CONTENTS

Trade Shows: Why We Love (Hate) Them

Derek G. Hennecke, MBA, continues with part 5 of this 6-part series on business models and best practices for navigating the new normal.

Decade in Review – Drug Delivery Company Performance

Josef Bossart, PhD, examined sales of DDEPs throughout the past decade in his previous column and observed there were quite a few billion dollar babies. In this installment, he reviews how this has impacted the revenue and profits of drug delivery companies that provide partners with proprietary technology resources and drug delivery-enabled products.

Biopharmaceutical Drug Delivery: Going Beyond Injection

Frost & Sullivan Analyst Katheryn Symank reports that biopharmaceuticals have almost exclusively been delivered via parenteral administration, and as the demand for these products increases, so does interest in utilizing more convenient, non-invasive delivery routes.

 

Dendrimers: An Emerging Therapy for Cancer

Hitesh Patel, MPharm; Jayvadan Patel, PhD; Ravi Patel, MPharm; and Kalpesh Patel, MPharm; indicate that due to their multivalent and monodisperse character, dendrimers have stimulated wide interest in the field of chemistry and biology, especially in applications such as drug delivery, gene therapy, and chemotherapy.

 

Nuchal Topical Neuro-Affective Therapy: A Novel Treatment for Parkinson’s Disease Using Apomorphine

Ronald Aung-Din, MD, reports significant preliminary open-label findings in an outpatient office setting that suggest potential utility for nuchal Apo therapy in the management of Parkinson’s disease.

 

Fast LC/MS/MS Methods Using Restricted Access Media (RAM) Guard Columns & Switching Valves

Venkata Boppana, MPharm, explains how an automated on-line sample preparation system can be successfully coupled to an LC-MS-MS to develop and validate high-sensitivity analytical methods for diverse analytes in a very short time.

 

Technology Infrastructure to Promote Product Licensing Exchange

Joel Finkle reviews the established standards of Clinical Data Interchange Standards Consortium data, structured product labeling for product data, and the Electronic Common Technical Document submission format, as well as other technologies still under development.

 

DisperSol Technologies: Achieving Drug Solubility Using Solid Dispersion

Drug Delivery Executive: Yaniv Gershon, President and CEO of DisperSol Technologies, speaks about the advantages that KinetiSol^® Solid Dispersion brings to the drug delivery market.

 

Gateway Analytical: Conventional & Novel Analytical Testing Services for Drug Development

Executive Summary: David Exline, Senior Vice President of Gateway Analytical, discusses the company’s launch, the needs its services address in the marketplace, as well as its role in drug formulation.

 

Oncolytic Viruses: The Future of Cancer Therapy?

Douglas W. Loe, PhD, MBA, says there are a number of oncolytic viruses that have shown potential use in cancer treatment, and demand for more effective agents is strong. Future research studies will offer an even clearer perspective on which, if any, of these viruses offer the most effective route toward a reliable and commercially viable complement to chemotherapy.

 

DEPARTMENTS

 

Market News & Trends

 

Excipient Update

Very Fine Chitosan Microparticles With Narrow & Controlled Size Distribution Using Spray-Drying Technologies

 

Technology Showcase

 

External Delivery

Don’t Burrow Down Into Obscurity!

 

COVER

FEATURES