May 2008

TABLE OF CONTENTS

Personal Guarantees: The Bad & The Evil

Derrek G. Hennecke, MBA, continues with part 4 of his 7-part series chronicling the challenges, issues, and more importantly, the opportunities he faced throughout his Management Buy-Out. 

P.L.E.A.S.E. (Painless Laser Epidermal System): A New Laser Microporation Technology

Yogeshvar N. Kalia, PhD; Yogeshwar G. Bachhav, PhD; Thomas Bragagna; and Christof Böhler, PhD; introduce a novel technique for the controlled poration of the epidermis and report initial results demonstrating its ability to increase the transport of difficult-to-deliver small molecule and peptide therapeutics across the skin.

 

Can the Systemic Pulmonary Delivery Market Breath Easy?

Contributor Cindy H. Dubin learns from some of the industry’s top players that despite a road filled with numerous opportunities in pulmonary delivery, experts are still striving to overcome the roadblocks along the way.

 

A Comparative Study of the Effect of Using Different Drying Techniques for Preparation of Inhalable Protein Powders on Their Aerosolization Performance

Magda Samaha, PhD; Ferial El-Khawas, PhD; Hoda El-Maradny, PhD; and Doaa Mohamed Ragab, PhD; compare three different methods for preparation of inhalable dry powders with respect to their aerosolization performance.

 

In Vivo Performance Assessment of Inhalation Devices

Peter D. Scholes, PhD, and Karen Jones, PhD, look at the increasing role gamma scintigraphy can play in optimizing inhaled devices and understanding how device/molecule/formulation variables impact delivery efficiency.

 

Development of Sustained Release Solid Dispersions Using Factorial Design

A.K. Madan, PhD; Harish Dureja, MPharm; and Monika, MPharm; developed in this present study a mathematical model that can be used to predict the cumulative percent of Glibenclamide released from SRSDs.

 

The “New” Emisphere: Impacting the Future of Drug Delivery

Drug Delivery Executive: Michael V. Novinski, President and CEO of Emisphere, discusses the company’s technology, product pipeline, and its future strategic direction.

 

What You Need to Know About Hiring a Protein & Peptide Contractor
Contributor Cindy H. Dubin asked some of today’s leading contractors to describe how they are working with Specialty Pharma clients to deliver new and complicated products to the market quickly and cost efficiently.

 

Southern Research Supports Drug Discovery & Development

Executive Summary: Nancy Gray, VP of Corporate Development for Southern Research speaks about how the Drug Discovery and Development divisions have worked to discover, screen, and develop new drugs and vaccines for cancer, HIV, hepatitis, tuberculosis, influenza, central nervous system diseases, and neurological disorders.

 

Oncology Therapeutics: A New Solution for Anthracycline Extravasation
Lisa Schulmeister, RN, MN, describes the small patient population suffering from anthracycline extravasation and how one company, TopoTarget, has developed a product that helps reverse the severe tissue damage.

 

DEPARTMENTS

 

Market News & Trends

 

Advanced Delivery Devices

New Guidelines for Reconstituted Drug Devices

 

Technology Showcase

 

Facts & Figures

 

External Delivery

The Glamour of Flying

                                                                                                                       

COVER

FEATURES