Analytical Testing

IMAGE-BASED CHARACTERIZATION - Non-Invasive, Quantitative Characterization of Lyophilized Drug Product Using Three-Dimensional X-Ray Microscopy Analytics

Shawn Zhang, PhD, Johnathan Goldman, PhD, Xiaodong Chen, PhD, et al present a new method that not only characterizes quantitatively the microstructures of the lyophilized drug samples, but also presents the potential to correlate the microstructures with physical properties to optimize parameters in drug formulation, cycle development, process scale-up, stability control, and administration.

Frequently Asked Questions About Analytical Testing

What are the latest trends in analytical testing for pharmaceuticals?

Recent trends include advanced automation in lab processes, predictive in silico modeling, and the adoption of diverse analytical techniques to support evolving biologics, inhaled therapies, and personalized medicines.

How are CDMOs improving resilience in analytical supply chains?

CDMOs are using multi-sourcing strategies, expanding vendor bases, and implementing flexible automation solutions to mitigate risks related to material shortages, tariffs, and geopolitical disruptions.

What role does automation play in modern analytical labs?

Automation solutions—such as semi-automated inhaled product testing and plug‑and‑play instruments—are enhancing accuracy, efficiency, and agility in testing workflows.