ACS Treatment Market to More Than Triple From $12.3 Billion to $43.4 Billion
The launch of several drugs with “extraordinary blockbuster potential” will cause the acute coronary syndrome (ACS) treatment market to more than triple in value, from $12.3 billion in 2013 to $43.4 billion by 2023, according to research and consulting firm GlobalData.
The company’s latest report, PharmaPoint: Acute Coronary Syndrome – Global Drug Forecast and Market Analysis to 2023, states that across seven major markets (the US, France, Germany, Italy, Spain, the UK, and Japan), there are three monoclonal antibodies (mAbs), all PCSK9 inhibitors, with the potential to reshape the post-ACS, dyslipidemia landscape.
Amgen’s evolocumab, Sanofi and Regeneron’s alirocumab, and Pfizer’s bococizumab are all demonstrating safe and significant reductions of serum LDL-C levels in major clinical trials, and GlobalData expects these treatments to be launched in the middle of the forecast period.
Eric J. Dimise, PhD, GlobalData’s Analyst covering Cardiovascular and Metabolic Disorders, says “These three mAbs, which fulfill a critical unmet need by offering novel approaches to LDL-C reduction for patients who cannot tolerate statins, are likely to be prescribed long-term, marking the first time that biologics will enter the mainstream of chronic ACS treatment. The premium price of PCSK9 mAbs means that they will be able to achieve substantial sales with a relatively small patient population. We forecast that they will account for around 40% of ACS sales by 2023, with a global value that slightly exceeds $17.5 billion.”
GlobalData has also identified two new anticoagulants, Janssen’s Xarelto and Merck’s Zontivity, which are both on track to compete directly with warfarin and post impressive sales over the next 9 years.
Dr. Dimise adds “Xarelto is anticipated to achieve approval for the ACS indication in the US by 2018. When added to the drug’s mounting sales in the EU, this will result in peak-year sales approaching $8 billion for ACS alone. Meanwhile, the PAR1 inhibitor, Zontivity, which enters the US market in Q3 of 2014, could achieve worldwide sales exceeding $1 billion by 2015. The dramatic increase in overall ACS market value is attributable to the launch of these and several other drugs currently in the late-stage development pipeline, all of which have extraordinary blockbuster potential.”
PharmaPoint: Acute Coronary Syndrome – Global Drug Forecast and Market Analysis to 2023
This report provides an overview of Acute Coronary Syndrome (ACS), including epidemiology, etiology, pathophysiology, symptoms, diagnosis, and treatment guidelines. The key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, pipeline analysis, and implications for the ACS therapeutics market. This report was built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis conducted by GlobalData’s team of industry experts.
GlobalData is a leading global research and consulting firm offering advanced analytics to help clients make better, more informed decisions every day. Our research and analysis is based on the expert knowledge of over 700 qualified business analysts and 25,000 interviews conducted with industry insiders every year, enabling us to offer the most relevant, reliable and actionable strategic business intelligence available for a wide range of industries. For more information, please contact our Press Office on +44 (0)1204 543 537 or at pr@globaldata.com.
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