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March 2013

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COVER

DRUG DELIVERY – Oral Delivery of Peptides by Peptelligence Technology

William Stern, PhD; Nozer Mehta, PhD; and Stephen Carl, PhD; review a highly developed, clinically proven platform technology that enables the oral delivery of peptides, overcoming the hurdles inherent to oral peptide delivery.

FEATURES

FORMULATION DEVELOPMENT – Bioavailability Enhancement Strategies & Opportunities

Frost & Sullivan Analyst Ruplekha Choudhurie reviews some BA approaches that are being developed by a number of companies that can mitigate the biological, physical, and chemical barriers for effective delivery of poorly soluble and permeable drugs.

SPECIAL FEATURE – Analytical Instrumentation Gets Faster, Smaller, and Easier to Use

Contributor Cindy H. Dubin learns that one doesn't have to be a rocket scientist to use analytical instrumentation. Three leading players in the market showcase their products, all aimed at making analysis easier and faster.

EXECUTIVE INTERVIEW – AAIPharma: Making the CDMO a One-Stop-Shop for Manufacturing, Development & Analytical Services

Drug Development Executive: Patrick Walsh, CEO, and Board Director of AAIPharma Services Corp., talks about the role of a CDMO in today's pharma and biotech space, why companies may choose to partner with a CDMO, and how the company has managed to maintain a leading position in the market.

DRUG DEVICES – Intranasal Saline: Can a Spray Per Day Keep the Doctor Away?

Degenhard Marx, PhD, and Georges Bouille provide an overview and discussion of the benefits of using intranasal saline, and a range of different devices on the market allowing administration into the nose.

MANAGEMENT INSIGHT – Business Lessons From the Salamander

Derek G. Hennecke continues with part 2 on a new 6-part series offering an overview of this year’s best business books with insights into what they can teach the Pharma industry.

CONTRACT SERVICES – Maximizing Yield in Transdermal Manufacturing

James Fenton says that while the challenges presented by manufacturing pain management products can be significant for some manufacturers, for the right manufacturer, pain management products can present an ideal opportunity.

DELIVERY DEVICES – The New Industry Paradigm for Prefilled Success

Alan Shortall indicates that following a period of relative industry stability defined by peripheral innovation, a converging series of external and internal forces are set to reshape the prefilled syringe industry so that it will better serve the emerging needs of pharmaceutical companies, patients, and other stakeholders across the continuum of care.

DRUG DELIVERY – Oral Delivery of Peptides by Peptelligence Technology

William Stern, PhD; Nozer Mehta, PhD; and Stephen Carl, PhD; review a highly developed, clinically proven platform technology that enables the oral delivery of peptides, overcoming the hurdles inherent to oral peptide delivery.

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