Formulation Development
Global Regulators Discuss Observational Studies of Real-World Data for COVID-19 Medicines
In a recent dedicated COVID-19 workshop, organized by the European Medicines Agency (EMA) under the umbrella of the International Coalition of Medicines Regulatory Authorities (ICMRA),…
Emisphere Announces Novo Nordisk Development Update
Novo Nordisk recently announced the European Commission (EC) has granted marketing authorization for Rybelsus, (oral semaglutide), for the treatment of adults with insufficiently controlled type…
Antiviral Drugs Market to Foresee Tremendous Gains Over 2020-2026
The global antiviral drugs market was valued at $56 billion in 2019 and is expected to accrue phenomenal gains over the forecast period. The spread…
Metrion Biosciences & International Scientific Consortium Publish Data & New Recommendations for In Vitro Risk Assessment of the Cardiac Safety of New Medicines
Metrion Biosciences Limited announced it has contributed to two new peer-reviewed papers under the US FDA CiPA (Comprehensive in vitro Proarrhythmia Assay) initiative. The papers,…
Novavax Identifies COVID-19 Vaccine Candidate; Accelerates Initiation of First-in-Human Trial to Mid-May
Novavax, Inc. recently announced it has identified a coronavirus vaccine candidate, NVX-CoV2373, a stable, prefusion protein made using Novavax’ proprietary nanoparticle technology, and will initiate…
For a CDMO, Flexibility & Adaptability Are Key Attributes to Navigate the Evolving Healthcare Landscape
The healthcare landscape continues to change at a rapid pace. The strong growth in the number of complex drugs, new therapeutic approaches and technologies, pricing issues and….
NeuBase Therapeutics Announces Positive Preclinical Data
NeuBase Therapeutics, Inc. recently announced positive preclinical data from its pharmacokinetics studies in non-human primates (NHPs) and in vitro pharmacodynamics data in patient-derived cell lines.…
Oxford BioTherapeutics Announces Second Oncology Drug Candidate Selected to Advance Into Formal IND-Enabling Studies From Boehringer Ingelheim Collaboration
Oxford BioTherapeutics Ltd. recently announced that Boehringer Ingelheim has selected a second asset to advance into formal IND enabling studies. The asset discovery was enabled…
New Incentives & Benefits Can Boost R&D Ecosystem for New Drug Development in India
India has recently sought feedback from the top pharmaceutical companies to make regulatory changes that offer specific tax benefits for specialized research. With the government’s…
Malvern Panalytical & Concept Life Sciences Form Unique Partnership
Malvern Panalytical and Concept Life Sciences recently launched a new partnership that combines advanced instrumentation with expert analytical services for discovery and development. This collaboration…
Aravive Announces AVB-500 Improves Anti-Tumor Effects When Combined With Anti-Angiogenic Bevacizumab or PARP Inhibitor Olaparib
Aravive, Inc. recently announced that AVB-500 improves anti-tumor effects when combined with the anti-angiogenic bevacizumab or the PARP inhibitor olaparib in preclinical uterine cancer models.…
Carterra Selected by La Jolla Institute of Immunology to Provide Antibody Screening & Characterization for the Coronavirus Immunotherapy Consortium (CoVIC)
Carterra Inc. and La Jolla Institute for Immunology (LJI), announced today that they will use Carterra’s proprietary LSA platform to screen hundreds of antibodies in…
Saama Makes State-of-the-Art Clinical Analytics Platform Available to Integrate Data From All Organizations Investigating COVID-19 Treatments
Saama Technologies, Inc. recently announced it will contribute its AI-powered Life Science Analytics Cloud (LSAC) technology platform to establish the EndPandemic National Data Consortium…..
Horizon Discovery & Pharmahungary Report Positive Early Stage Results for Novel Micro-RNA Therapeutic
Horizon Discovery Group plc and Pharmahungary Group recently announced positive early stage results for a novel micro-RNA therapeutic for…………..
Altimmune & the University of Alabama Collaborate on Development of Single-Dose, Intranasal COVID-19 Vaccine
Altimmune, Inc. recently announced it is launching a collaboration with the University of Alabama at Birmingham (UAB) on the development of its single-dose…..
SPECIAL FEATURE - Excipients: Matching Ingredients to Molecules Improves Functionality
Contributor Cindy Dubin speaks with several leading excipient manufacturers on how their excipient offerings are improving drug release, solubility, taste, physical characteristics, viscosity, and more for a range of molecules.
FORMULATION FORUM - Rational Design & Development of Lipid-Filled Hard Capsules
Jim Huang, PhD, says with ever increasing percentage of water-insoluble or low permeable new therapeutic entities among drug pipelines, lipid-based delivery systems, together with other main delivery technologies, have become an important tool for the development of those compounds.
THERAPEUTIC PEPTIDES - Continuous Manufacturing of Peptides Could Speed Up Development, Reduce Costs & Improve Quality
Jens Bukrinski, PhD, MSc, says the high-quality, high-process consistency between manufacturing runs and the in-line PAT analytics of the μLOT platform will enable unprecedented robustness of the manufacturing process, significantly retiring the risk of failure to supply due to non-scalability of the manufacturing process.
CANNABINOID THERAPY - NeuroDirect Effects(TM) CBD: Non-Systemic Cannabidiol for Autism Spectrum Disorder
Ronald Aung-Din, MD, says NeuroDirect Effects Technology CBD is particularly attractive in this population as it utilizes the body’s own ECS, and in utilizing a non-systemic therapeutic mechanism, there is less likelihood for long-term negative effects in developing brains of children.
ORAL THIN FILMS - Misconceptions, Advantages & Limitations About an Emerging Drug Delivery System
Srinivasan Shanmugam, PhD, says due to advancements in the science behind OTF design, as well as the predicted increase in OTF market valuation, this drug delivery system is becoming increasingly popular.
