Dalton Pharma Services Enters Drug Development & Manufacturing Services Agreement
Dalton Pharma Services recently announce a drug development and manufacturing services agreement with ExCellThera Inc. This agreement provides ExCellThera access to Dalton’s state-of-the-art cGMP, Health Canada approved biopharmaceutical facility in Toronto, Ontario, Canada. Under the agreement terms, Dalton will be responsible for the formulation and fill/finish of UM171, a constituent of ExCellThera`s lead technology, ECT-001, to support Phase II clinical trials in Canada and the US.
Stem cell transplantation is a medical procedure that could increasingly be used in the treatment of blood and bone marrow cancers and shows potential for autoimmune disorders and other non-malignant diseases. ECT-001 is a combination of a small molecule, UM171, and an optimized culture system. The technology, capable of expanding the number of stem and immune cells exponentially in as little as 7 days, is used in novel curative cord blood transplant therapies for patients with blood cancers, allowing more rapid engraftment, greatly reduced incidence of transplant-related mortality, low risk of chronic graft-versus-host disease and low risk of relapse, resulting in better outcomes for patients.
“Dalton is pleased to apply its expertise in aseptic formulation and sterile fill/finish toward developing this leading-edge therapy. We look forward to working with ExCellThera in support of their efforts to develop ECT-001 as a treatment for blood cancers.” said Peter Pekos, CEO of Dalton Pharma Services.
ExCellThera is a clinical-stage biotechnology company delivering molecules and bioengineering solutions to expand stem and immune cells for use in novel one-time curative therapies for patients with hematologic malignancies, autoimmune and other diseases. ExCellThera’s lead solution combines a proprietary small molecule, UM171, and an optimized culture system. In pursuit of better treatments for patients, the company is building out its portfolio of products, as well as supporting best-in-class clinical trials. For more information, visit https://excellthera.com.
Dalton Pharma Services is a leading North American cGMP pharmaceutical organization providing integrated drug discovery, development, and manufacturing services. We are FDA registered and Health Canada approved and bring over 30 years of experience to every project. We deliver fully integrated solutions with an emphasis on speed, flexibility, and quality. Our integrated services (drug discovery, formulation and process development, custom synthesis, cGMP sterile fill/finish of liquids and powders, cGMP API manufacturing and/or dosage form manufacturing and Accelerated Stability Testing) all at one location helps us to be adaptable, flexible and cost-effective. For more information, visit www.dalton.com.
Total Page Views: 1512
