Kythera Biopharmaceuticals Raises $37.4-Million Financing


KYTHERA Biopharmaceuticals, Inc. recently announced the closing of a $37.4-million Series D financing. The round featured significant new investments as well as participation from all existing institutional investors. Proceeds from this financing are slated to be used for conducting US Phase III trials for KYTHERA’s lead product, ATX-101, a first-in-class, injectable drug that is under investigation for the reduction of submental (under the chin) fat.

“We are delighted to once again have attracted the support of top flight investors in pursuit of our vision of building a premiere science-based aesthetic medicine company,” said Keith Leonard, KYTHERA’s President and CEO. “We also appreciate the continued support and commitment from our existing investors.”

KYTHERA’s investors include Versant Ventures, ARCH Venture Partners, Prospect Venture Partners, JAFCO, Partner Funds Management (PFM), INVUS Financial Advisors, BBT Capital Management/Apothecary Capital, and Altitude Life Science Ventures. Also joining the syndicate were Foley Ventures and Latham and Watkins. KYTHERA has now raised more than $108 million in four rounds of private financing.

“These new investments are a further powerful validation of KYTHERA’s novel, biotechnology-based approach to aesthetic medicine,” added Mr. Leonard. “We believe this new round of financing in today’s volatile economy is a testament to the robust scientific foundation of our lead product candidate and the promise of its future potential.”

KYTHERA has completed extensive development work on ATX-101 for the reduction of submental fat, completing seven clinical trials with more than 350 subjects. European Phase III studies of ATX-101 were initiated in late 2010 (enrolled more than 700 subjects) in collaboration with Bayer HealthCare’s dermatology unit Intendis, which has licensed rights to ATX-101 outside of the US and Canada.

KYTHERA Biopharmaceuticals, Inc. is a privately held, clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel prescription products for the aesthetic market. KYTHERA has an innovative pipeline, with its lead program in adipolysis (ATX-101) projected to start US Phase III trials late in 2011 or early 2012. The company also has active research programs with focused interest in hair and fat biology, pigmentation modulation, and facial contouring.