issues

November / December 2012

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COVER

CONTRACT SERVICES – Industry Trends: Outsourcing Pharmaceutical Development & Innovation

Frost & Sullivan Analysts Winny Tan, PhD, and Jennifer Brice highlight two dynamic pharmaceutical service segments, CROs and IVD manufacturers, and how they are evolving to meet the growing preclinical and clinical trial needs of pharmaceutical companies. They also discuss open innovation models for outsourcing the earliest stage of drug discovery.

FEATURES

GLOBAL BIOSIMILARS MARKET – Large Opportunity Due to Patent Expiries of Blockbuster Biologics

Frost & Sullivan Analysts Jennifer Brice and Deborah Toscano observe how the arrival of biosimilars, or highly similar copies of biopharmaceutical products, to the US market is imminent, and although they have been available elsewhere for several years, physicians and other key stakeholders in the US have only recently begun to anticipate their arrival.

ANALYTICAL TESTING – Improvements in Characterization of Pharmaceuticals: Fast Scanning Rate DSC Methods

Kevin P. Menard, PhD, MBA, says fast scanning rate DSC represents a recent and underutilized technique for the characterization of pharmaceutical materials and highlights several of the more common applications.

FORMULATION DEVELOPMENT – KinetiSol: A New Processing Paradigm for Amorphous Solid Dispersion Systems

Dave A. Miller, PhD; James C. DiNunzio, PhD; Justin R. Hughey, PhD; Robert O. Williams III, PhD; and James W. McGinity, PhD; review how a novel fusion-based process for the production of amorphous solid dispersion systems has recently been adapted to pharmaceutical processing and is providing novel solutions for difficult-to-process compounds.

EXECUTIVE INTERVIEW – Novozymes Biopharma: Improving Drug Safety & Stability With Recombinant Human Albumin

Mark Perkins, Customer Solution Manager at Novozymes Biopharma, discusses how the company is improving the formulation of many new drugs and offering customers new ways of achieving a competitive advantage.

DRUG DELIVERY – Recent Advancements in Drug Delivery: Novel Formulations & Technologies Offer Improved Treatment Options

Debbie Toscano, Senior Industry Analyst, Frost & Sullivan, highlights a few recent innovative approaches to drug delivery with a focus on some of the therapeutic areas most relevant to the current pharmaceuticals market.

DRUG DEVICES – The Future of DPIs: Aligning Design With Market Demands

Gerallt Williams, PhD, takes a look at the market forces driving DPI innovation and focuses on a novel solution that has simplicity at the heart of its design, and which hopes to address the growing pressure to reduce healthcare costs, as well as the needs of new markets, arising from emerging economies in South America, India, and China.

PACKAGING – The Impact of Packaging at the Clinical Interface of Vaccine, Healthcare Worker & Patient

Brian Lynch, MBA; and Philip Song, MSc; indicate further adoption of vaccines packaged in PFS is expected to continue, for both new and currently marketed vaccines, particularly as clinicians and vaccine enterprise stakeholders look more closely at the implication of packaging at the user interface and understand the benefits PFS offer in terms of greater efficiency and advancing best care.

CONTRACT SERVICES – Industry Trends: Outsourcing Pharmaceutical Development & Innovation

Frost & Sullivan Analysts Winny Tan, PhD, and Jennifer Brice highlight two dynamic pharmaceutical service segments, CROs and IVD manufacturers, and how they are evolving to meet the growing preclinical and clinical trial needs of pharmaceutical companies. They also discuss open innovation models for outsourcing the earliest stage of drug discovery.