May 2012

TABLE OF CONTENTS

ANALYTICAL TESTING – Diffusion Kinetics & Permeation Concentration of Human SC Characterization by Terahertz Scanning Reflectometry

Anis Rahman, PhD; Scott Frenchek; Brian Kilfoyle; Leena Patterkine, PhD; Aunik Rahman; and Bozena Michniak- Kohn, PhD; use terahertz reflectometry and spectrometry to investigate the permeation kinetics and concentration profile of active ingredients into the stratum corneum.

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EXECUTIVE INTERVIEW – Evonik: Supporting Development & Commercial Cycles of Injectables

Dr. Jean-Luc Herbeaux, the Head of the Health Care Business Line of Evonik, discusses the rationale and success of his company’s latest acquisition.

EXECUTIVE INTERVIEW – Ezose Sciences: High-Throughput Glycomics for Biomarker Discovery – Bringing Glycan Analysis Into Everyday Research

Scott Siegel, PhD, VP of Business Development at Ezose, discusses how his unique company is catalyzing progress across an emerging research front.

MANAGEMENT INSIGHT – Fiat, Help Remedies, Drug Guarantees, Golf Courses

Derek G. Hennecke continues with part 3 of his 6-part series on lessons learned from other industries.

EXECUTIVE INTERVIEW – Bend Research: Problem-Solving in the Pharmaceutical Industry

Dr. Rod Ray, CEO and Chairman at Bend Research, discusses his company’s approach to difficult drug delivery challenges and the core technologies offered by his company.

SPECIAL FEATURE – Prefilled Syringes – A Container of Choice for Pharma

Contributor Cindy H. Dubin interviewed leading players in the prefilled syringe market to find out about their offerings and how they are addressing pharma’s needs for safety, ease of use, cost, and product differentiation.

THERAPEUTIC FOCUS – Rheumatoid Arthritis Meets Its Match

Jos Raats, PhD, says ModiQuest has undertaken a number of studies into specific anti-Citrulline antibodies and has discovered a subset (family) of rCit-hMabs, which could provide a valuable therapeutic in the treatment of early onset RA.

ANALYTICAL TESTING – Diffusion Kinetics & Permeation Concentration of Human SC Characterization by Terahertz Scanning Reflectometry

Anis Rahman, PhD; Scott Frenchek; Brian Kilfoyle; Leena Patterkine, PhD; Aunik Rahman; and Bozena Michniak- Kohn, PhD; use terahertz reflectometry and spectrometry to investigate the permeation kinetics and concentration profile of active ingredients into the stratum corneum.

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