New Parsum IPP-80 In-Line Particle Sizing Probe: Robust, Trouble-Free Granulation Monitoring


The new Parsum IPP-80 probe from Malvern Instruments brings easy to integrate inline particle size measurement for efficient process monitoring and control. Suitable for powders, pellets and granules the new probe enables the real-time monitoring of agglomeration, coating and granulation processes. The resulting data provide a secure basis for pilot plant studies, process optimization and control. A robust, sanitary design delivers long-running operation with minimal attention and includes in-built self-diagnostic tools that ensure data quality.

The new Parsum IPP-80 probe from Malvern Instruments

For many products, including many pharmaceuticals and foods, particle size is a performance defining characteristic. During granulation, for example, control of particle size may be vital, to ensure the production of granules that meet the requirements of subsequent processing steps and/or deliver the required performance in a finished product. Inline PSD measurement enables robust process monitoring and control. In the pharmaceutical industry these capabilities support the application of QbD, scoping of the Design Space and the development of continuous manufacturing in line with recent FDA guidance.

The Parsum IPP-80 inline probe provides continuous particle size and size distribution data, via the technique of spatial filter velocimetry. Measuring in the range of 50 µm to 6000 µm the probe is able to robustly analyze powders as well as pellets and large granules. It has been fully optimized to meet the rigors of the process environment and has no moving parts or user-accessible components. Extremely stable optics mean that the probe is resistant to the effects of vibration and requires no manual alignment. The software includes a range of diagnostic features for measurement verification and self-diagnosis to ensure trouble-free operation and safeguard data quality. The Parsum IPP-80 has been specified for use in an environment where hygiene is a priority and has a sanitary stainless steel design that is easy to clean with any conventional cleaning agent. It is ATEX certified for Zone 0/20 operation.

For more information on Parsum IPP-80, view the launch webinar here http://www.malvern.com/parsum-webinar.

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About Malvern Instruments

Malvern provides the materials and biophysical characterization technology and expertise that enables scientists and engineers to understand and control the properties of dispersed systems. These systems range from proteins and polymers in solution, particle and nanoparticle suspensions and emulsions, through to sprays and aerosols, industrial bulk powders and high concentration slurries. Used at all stages of research, development and manufacturing, Malvern’s materials characterization instruments provide critical information that helps accelerate research and product development, enhance and maintain product quality and optimize process efficiency.

Our products reflect Malvern’s drive to exploit the latest technological innovations and our commitment to maximizing the potential of established techniques. They are used by both industry and academia, in sectors ranging from pharmaceuticals and biopharmaceuticals to bulk chemicals, cement, plastics and polymers, energy and the environment.

Malvern systems are used to measure particle size, particle shape, zeta potential, protein charge, molecular weight, mass, size and conformation, rheological properties and for chemical identification, advancing the understanding of dispersed systems across many different industries and applications.

Headquartered in Malvern, UK, Malvern Instruments has subsidiary organizations in all major European markets, North America, China, Japan and Korea, a joint venture in India, a global distributor network and applications laboratories around the world. www.malvern.com

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