Kyowa Kirin Announces Board Approval for Construction of New Biologics Manufacturing Plant in Sanford, NC

Kyowa Kirin, Inc., an affiliate of Kyowa Kirin Co., Ltd. (Kyowa Kirin, TSE: 4151), a global specialty pharmaceutical company based in Japan, recently announced that its board of directors has approved plans to invest up to $530 million to build a new, state-of-the-art manufacturing facility in Sanford, North Carolina. The 171,700-square-foot, two-reactor facility will accelerate the company’s development and production of biologic therapies for patients with rare and serious diseases while also contributing to the Sanford area’s economic growth and development.

“The extraordinary complexity of the medicines we manufacture requires specialized skills and resources that are in plentiful supply in Sanford and the Research Triangle region,” said Paul Testa, Executive Vice President, Regional Head North America/EMEA Manufacturing, Kyowa Kirin North America. “We’re excited to collaborate with area colleges, universities, businesses, and civic leaders to ensure that our plans align with Sanford’s vision for growth, anchored in a rejuvenated manufacturing economy that offers diverse job opportunities and returns value to the community.”

A key driver of the new manufacturing facility is the growing global imperative to treat diseases that individually are rare, but which collectively affect an estimated 263 to 446 million people worldwide. Kyowa Kirin is uniquely positioned to fulfill the unmet needs of patients living with rare and underserved diseases by continuing to build on its more than 70-year history of discovering and developing novel medicines that offer life-changing value to patients.

The new facility will manufacture innovative biologic therapies, including next-generation antibodies, for the company’s planned clinical trials and future commercial use while creating more resilient and efficient supply lines that more readily withstand shifting global forces. The 75-acre campus at Helix Innovation Park at The Brickyard will allow for future expansion, should the company’s portfolio necessitate greater capacity as its pipeline programs advance.

Construction of the facility is expected to begin in the second half of 2024 and become fully operational in 2027. Kyowa Kirin’s investment of up to $530 million will be supported by performance-based state and local incentives to Kyowa Kirin of $10 million over 12 years, which are estimated to grow the state’s economy by $1.05 billion over the course of grant, according to the North Carolina Department of Commerce. The plant will create more than 100 new local jobs at an average salary of $91,496.

“Our North American presence continues to grow through strategic investments that are adding new capabilities, new therapeutic expertise, and new talent to our global organization, all in service of meeting patients’ needs,” said Steve Schaefer, Kyowa Kirin North American President. “Among the many qualities that drew us to North Carolina are our shared values, such as harmony and teamwork¾known as Wa, which is deeply engrained in our culture at Kyowa Kirin, evident in our longstanding corporate partnerships, and fundamental to high-quality pharmaceutical manufacturing.”

The Sanford facility will round out and enhance Kyowa Kirin’s global manufacturing network, which includes sites in Takasaki City, Gunma Prefecture, and Ube City, Yamaguchi Prefecture in Japan. By building its new site in the midst of North Carolina’s robust life sciences hub, Kyowa Kirin will benefit from a thriving network of biomanufacturing resources as well as a rich pool of talent within the greater Research Triangle Park region, which is home to renowned universities and community colleges that provide specialized curricula and training. The new facility will leverage the expertise of these institutions and build upon the manufacturing methods and technologies recently added in Takasaki to further enhance manufacturing productivity and efficiency.

“I am very excited that Kyowa Kirin is constructing a new manufacturing plant for biologics drug substance in the US,” said Toshiyuki Kurata, Chief Supply Chain Officer, and Global Manufacturing Head at Kyowa Kirin. “The new facility will be scalable with our Takasaki Plant in Japan to help ease technology transfer between the two plants and add production capacity. We believe this will help accelerate drug development and production.”

 Kyowa Kirin strives to create and deliver novel medicines with life-changing value. As a Japan-based Global Specialty Pharmaceutical Company with a more than 70-year heritage, we apply cutting-edge science including expertise in antibody research and engineering, to address the needs of patients and society across multiple therapeutic areas including Nephrology, Oncology, Immunology/Allergy and Neurology. Across our four regions – Japan, Asia Pacific, North America and EMEA/International – we focus on our purpose, to make people smile, and are united by our shared values of commitment to life, teamwork/Wa, innovation, and integrity. You can learn more about the Kyowa Kirin North America at: kkna.kyowakirin.com.