Metrics Contract Services Begins $10-Million Plant Expansion

Metrics Contract Services recently announced it has commenced construction on the expansion of its novel oral solid dosage manufacturing facility expansion in Greenville, NC. The $10-million investment will add 3,760 square feet of production space to the current facility, providing added flexibility and capacity to the CDMO and its clients.

The expansion consists of three new rooms: one dispensing/flex room, one tablet press room and one flex room to accommodate the company’s growing portfolio of commercial services following sustained increase in demand from clients for high potent handling capabilities.

New equipment also forms part of the investment and includes a Fette FE55 tablet press, a Bosch 720 encapsulator, which both offer containment capabilities for the safe handling of potent products, and a weigh and dispense isolator.

“The new equipment we’ve purchased is ideal for the small batch size and high changeover products which our clients require,” said John Ross, President at Mayne Pharma US and Metrics Contract Services. “Our clients will see immediate benefits through higher yields and improved potent handling. We recognized that customer’s commercial requirements often demanded increased flexibility within production suites. This expansion will cater for those needs because it creates more spaces where equipment trains can be tailored to the applicable process.”

The expansion project which has been in development over the past 6 months is expected to be complete and fully operational by February 2021.

Ross added “This is a significant investment for the business and reflects our commitment to increasing our novel oral solid manufacturing capabilities and providing our clients with quality services from initial concept through to global commercialization. We are now actively looking at the next phase of investment and how to maximise the expanded facility even further with the potential addition of further packaging and adjacent formulation technologies.”

Metrics Contract Services offers quality pharmaceutical formulation development; clinical trial materials manufacturing for all phases; analytical method development and validation services and commercial scale manufacturing and specializes in highly potent, novel oral solid dosage forms.

Metrics Contract Services is a full-service pharmaceutical development and manufacturing organization serving clients worldwide delivering proven scientific and operational excellence for novel oral dosage forms.

Metrics’ areas of expertise include quality pharmaceutical formulation development; first-time-in-human formulations; Phase 1-3 clinical trial materials manufacturing; and analytical method development and validation services leading to commercial scale manufacturing.

Technical capabilities include highly potent, cytotoxic and unstable compounds; Schedule II-V controlled substances; and products with poor bioavailability, for which we offer an impressive portfolio of advanced delivery methods. Located in Greenville, N.C., Metrics is a proud member of Mayne Pharma. For more information, visit metricscontractservices.com.

Mayne Pharma is an ASX-listed specialty pharmaceutical company focused on applying its drug delivery expertise to commercialize branded and generic pharmaceuticals. Mayne Pharma also provides contract development and manufacturing services to more than 100 clients worldwide. Mayne Pharma has a 40-year track record of innovation and success in developing new oral drug delivery systems and these technologies have been successfully commercialized in numerous products that continue to be marketed around the world. Mayne Pharma has two product development and manufacturing facilities based in Salisbury, Australia and Greenville, USA with expertise in the formulation of complex oral and topical dose forms including potent compounds, modified-release products and poorly soluble compounds. For more information, visit maynepharma.com.