Proveris Scientific  – Testing True Product Performance

Leader in analytical instruments for spray and aerosol product testing and contract services. Trusted partner in product development from early stage R&D to manufacturing. Serving pharmaceutical companies, device manufacturers, CDO/CRO/CMOs, and regulatory agencies.

Two Cabot Road, Hudson, MA 01749
T: +1 508 460-8822
E: contactus@proveris.com
W: www.proveris.com

Partners Through the Full Product Cycle:
Formulation Screening > Device Screening > Submission> QC Release Testing

Proveris Scientific  is an instrument and laboratory service company that creates today’s most advanced testing solutions for orally inhaled and nasal drug product (OINDP) drug development and manufacturing.

As partners to our clients we;

  • accelerate successful product development, and prevent late-stage development failures
  • realize significant savings in time and resources by streamlining testing workflows
  • evaluate the suitability of various OINDP delivery devices and optimize device parameters for maximum efficacy
  • optimize testing variables to maintain batch-to-batch reproducibility, simplifying regulatory submissions

LABORATORY SERVICES

The Proveris by Design™ process is the key to unlocking a successful product submission!

The unique, patented process employed by Proveris Laboratories is a launch point because it identifies the human usage performance of an OINDP according to current FDA and ICH guidelines for in vitro testing.

Lab Studies Offered:

  • Human Actuation Study
  • Method Development
  • Determining Optimum Actuation Profile
  • Reference Product Characterization
    – Shot Weight
    – Droplet Size Distribution
    – Spray Pattern
    – Plume Geometry
    – Plume Front Velocity
    – Spray Duration
    – Evaporation Rate
  • Device Screening
  • Formulation Screening
  • Regional Drug deposition (INVIDA)
  • Actuation Force Evaluation
  • Technology/Method Transfer

Device Types:

ANALYTICAL INSTRUMENTS

Innovative Testing Platforms Advance the Science of Nasal and Inhaled Drug Delivery

Proveris instruments expedite drug product analysis by effectively streamlining laboratory workflows and eliminating manual processes.

SprayVIEW® Measurement System
The industry standard for measuring and analyzing the spray pattern, plume geometry and plume front velocity produced by spray and aerosol generating devices. Watch Video

Vereo® Automated Actuators
Replicates human usage of spray and aerosol devices through reproducible, automated actuation to eliminate inconsistencies caused by manual testing. Watch Video

Indizo® Automated Nasal Spray Collection System
Fully automates the labor-intensive and error-prone tasks of spraying, weighing and sample collection for pump delivery and dose content uniformity testing with vertically-actuated and side-actuated nasal spray devices.

Kinaero CxTM pMDI Collection System
Improves sample collection consistency during pressurized metered dose inhaler (pMDI) testing. The system incorporates proven Vereo automated actuator technology to control parameters for inhaler shaking and actuation, shake-to-fire timing, and flow rate and can be used for both delivered dose uniformity (DDU) and aerodynamic particle size distribution (APSD) testing. Watch Video

KinaeroTM High-Throughput pMDI Fire-Down System
Precise, reproducible shaking and actuation for automated wasting of pMDI inhaler devices ensuring uniform dose delivery for through life testing. Watch Video

Viota® Software
Powerful, yet intuitive software platform that drives Proveris’ whole suite of instrumentation. The latest Viota 9 release includes the ability to perform Plume Front Velocity and Spray Duration measurements for pressurized metered dose inhalers (pMDIs) and Soft Mist Inhalers (SMIs).

Read study results that have informed our clients decision-making and success.

Whitepapers | Scientific Posters | Product Literature

Posted Date: 12/1/2024
This record has been viewed 91 times.