Micropore Technologies Inc.
2121 T.W. Alexander Drive, Suite 124
Morrisville, NC 27560  
T: (984) 344 7499

Micropore Technologies Limited 
Wilton Centre, Redcar, TS10 4RF, UK
T: +(44) 1642 438367
E:  camden.cutright@microporetech.com
W: www.microporetech.com
Twitter: @microporetech
LinkedIn: linkedin.com/company/micropore-technologies-ltd/

 

COMPANY DESCRIPTION

Micropore Technologies is a global process technology and service provider to the pharmaceutical industry featuring patented membrane emulsification equipment for the commercially scalable development of microspheres, nanoparticles, and emulsions used in a wide range of controlled release, sterile injectable drug products. Originally spun-out of Loughborough University’s internationally renowned chemical engineering department, the company’s global headquarters and technical center are located in Wilton Center, UK with offices and operations in the USA, India, South Korea & Japan supporting over a hundred clients and strategic partners.

OUR TECHNOLOGY & SERVICES

Micropore’s award-winning membrane emulsification technology allows our customers to produce mono-disperse emulsions, microspheres and nanoparticles, with the precision of microfluidics and more efficient output than conventional processes such as homogenization. We offer best in class formulation consultation and lab-scale preclinical feasibility trials through to supply of our laboratory and commercially scalable production equipment.

Proven benefits of our approach include:

  • Less set-up time, reduced raw materials, and maintenance cost
  • Mono-disperse microspheres that require less downstream processing
  • Ability to produce wide range of emulsions from complex coacervates to hydrogels
  • Same system for producing lipid nanoparticles and liposomes
  • Aseptic design and fully cGMP compliant

Capabilities

  • Early-stage formulation development
  • cGMP process consultation and scale-up from lab to commercial
  • Pre-clinical small batch production
  • Particle sizing, shape, and encapsulation efficiency analysis
  • Tech transfer of production hardware
  • Global technical support and troubleshooting
  • Higher product yields through less wastage
  • Reduced product degradation
  • Lower use of expensive production additives
  • Significantly improved production energy efficiency

For more information, visit: www.microporetech.com

VIDEOS

An Introduction to Micropore Technologies
A short two minute intro to Micropore’s unique particle engineering technology and the benefits it offers in formulating products across a wide range of sectors.

 

 

An Introduction to Micropore’s Emulsification Technology
A short explainer animation showing the principles behind Micropore’s membrane-based emulsification and encapsulation processes.

 

LINKS TO WHITE PAPERS

Phase Change Materials
Phase change materials (PCMs) allow the storage of large amounts of latent heat during phase transition. This white paper details their many benefits, the necessity of particle encapsulation in PCMs; and the benefits membrane-based particle formation.

 

 

 

Liposomes & Lipid Nanoparticles
This white paper describes the advantages of liposomes and lipid nano particles for the efficient delivery of therapeutic payloads in pharmaceuticals and the efficiencies that can be achieved using membrane emulsification to produce them.

 

 

 

Sustained Release PLGA Microspheres
Because of its unique properties PLGA is the most important polymer for drug encapsulation. This white paper describes how membrane emulsification devices, using the well-proven solvent evaporation method, are opening up new opportunities for PLGA-based products.

 

 

 

Hydrogels in Drug Delivery & Biomedical Engineering
Hydrogels possess the capability of protecting labile drugs from degradation, thus controlling their release properties. This white paper describes how membrane emulsification sidesteps the challenges of creating hydrogels with precise size control, forming perfectly spherical droplets in sizes less than 50 µm.

 

 

 

Core-Shell Coacervation in Drug Delivery
This white paper focuses on drug delivery using complex coacervation. Achieving an accurate target capsule size in an industrial setting can be a challenge. A preferred approach is a system, such as membrane emulsification, where the desired size characteristics can be defined in advance and the emulsion produced in a single pass.

 

 

 

Silica Particles
This white paper outlines how, through an improved continuous scalable sol-gel process, both micro- and mesoporous, near-monodispersed, spherical Mesoporous Silica Particles (MSPs), with high API load carrying potential, can be produced with a range of internal pores between 1 and 12 nm and an average surface area between 300 and 750 m2g-1.

 

 

 

API Crystallisation
Membrane crystallisation is a relatively new technique based on the use of a porous material as a semi-permeable barrier between two phases. This white paper describes how a membrane can be used to create supersaturation by solvent evaporation, antisolvent or reactant addition, and mixing with a colder solvent.