Featured Articles From The Current Issue
ANTIGEN-SCREENING SYSTEM - Perfecting the Promise of T Cell Therapies for Infectious Disease & Cancer
Jessica B. Flechtner, PhD, explains how the information and insights gleaned from ATLAS, Genocea has been able to successfully define targets of human T cell responses that become central to novel vaccines and immunotherapies, and demonstrate success in a clinical setting.


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Contributor Cindy H. Dubin reports how leading excipient manufacturers are overcoming their own R&D challenges to deliver innovative excipients that address problems associated with both large and small molecules.
Hywel Williams, PhD, Annabel Igonin, PhD, David Vodak, PhD, and Hassan Benameur, PhD, believe lipophilic salts are being explored in a number of different areas and one interesting application is their potential to boost API loading in lipid formulations.
Joseph S. Dillon, PhD, MBA, and Lainie Mulvanny discuss the transformation of CNTs into a unique composition of matter, marking a complete departure from the dirty, tangled micron bundles of CNTs that frustrated medical researchers for years.
Don Paul Kovarcik, MBA, and William Wittbold, MS, indicate that while protein therapeutics have enjoyed considerable commercial success throughout the past 3 decades, there still remain formulation and delivery challenges.
Ronald Aung-Din, MD, reports topical CBD is beneficial in treating symptoms of a number of neuropathic and psychiatric conditions. Individual clinical response varied depending on condition treated and on severity and longevity of symptoms, and overall, topical CBD therapy was well tolerated.
Tom Johnson says on the surface, rights management protection may look like another expense and another system to maintain, and while that may be true, it is a critical security component that delivers rapid and significant return on investment.
Ian Fotheringham, PhD, and Mathew Upton, PhD, report that Infections caused by antibiotic resistant bacteria are an ever-increasing threat to public health, creating an urgent, growing demand for the identification and development of new therapies.
Jean Pierre Wery, President of Crown Bioscience, discusses the requirement for more accurate research models in oncology research, focusing on PDX models that have the ability to more adequately represent the conditions and mechanisms of immunotherapy in human patients.
John A. Bermingham says it is not a matter of IF your business is going to be hacked but WHEN your business is going to be hacked, but the vast majority of businesses in the US do not have any plans in place for such an event.
Derek Hennecke says once we understand what happens in our brains as we weigh our options, we can extrapolate this knowledge and look with fresh eyes at how CDMOs, large pharma, and the industry make decisions.
Lilli Zakarija, MSME, MBA, cautions that while OTS devices are already “developed” and on the market, they should still go through the device development design control process from the perspective of the combination product, and then let the design control process determine if the device meets the specific requirements of the CP.
Xiaoyi Xu, MS, Chandreyee Das, PhD, and Michael Sturges, PhD, indicate that the phosphorylation of histidine has not been widely studied in mammalian cells, despite its discovery in bovine liver mitochondria, and ask the question, could the phosphorylation of histidine emerge as a therapeutically important pathway in mammals?
Exclusive Online Content
Co-Processed Excipients Benefit Market, Offer OpportunityCo-Processed Excipients Benefit Market, Offer Opportunity
The excipients market is pharmaceutical manufacturing dependent, and the demand for excipients is constantly changing according to the production needs of manufacturers’ business strategies, marketing environments, and consumer demand.

Hearty CAGRs for Global Cardiac Biomarker MarketHearty CAGRs for Global Cardiac Biomarker Market
The global cardiac biomarker market should see excellent growth rates among major regions due to the growing prevalence and incidence rates of cardiac diseases. BCC Research reveals in its new report that the Asia-Pacific (APAC) region, in particular, should see a substantial growth rate percentage well into the teens.

Pharmaceutical Industry Licensing Deals Soared to Record $46.2 Billion in 2015Pharmaceutical Industry Licensing Deals Soared to Record $46.2 Billion in 2015
Licensing deal values in the pharmaceutical industry rose by 37.1% year-to-year, from $33.7 billion in 2014 to $46.2 billion in 2015, driven primarily by Sanofi, which struck three licensing deals that totaled nearly $9 billion, according to research and consulting firm GlobalData.

Q&A: Scientific Advances Address Challenges Posed by Poor Solubility of Drug CandidatesQ&A: Scientific Advances Address Challenges Posed by Poor Solubility of Drug Candidates
At Metrics Contract Services, Dr. Michael DeHart manages all aspects of personnel and operations relating to formulating and manufacturing a client’s pharmaceutical materials for Phase I, II and III clinical trials. In this article, Dr. DeHart discusses how scientific advances are addressing challenges posed by the poor solubility or stability of drug candidates.

Pharmaceutical Companies Increasingly Looking to Innovate High-Risk, First-In-Class Products Pharmaceutical Companies Increasingly Looking to Innovate High-Risk, First-In-Class Products
With the cost of bringing a single novel drug to market estimated to be $2.6 billion in 2015, pharmaceutical companies are increasingly looking towards developing first-in-class treatments to maximize revenue and stay ahead of competition, according to business intelligence provider GBI Research.

​​Is Your Plastic Material Suitable for Pharmaceutical Use?​​Is Your Plastic Material Suitable for Pharmaceutical Use?
If you are considering registering plastic material with the FDA in a Drug Master File (DMF), evaluating the safety of that plastic is key.

Global Type 2 Diabetes Market Set to Almost Double to $58.7 BillionGlobal Type 2 Diabetes Market Set to Almost Double to $58.7 Billion
The global type 2 diabetes market is set to almost double from $31.2 billion in 2015 to $58.7 billion by 2025, representing a compound annual growth rate of 6.5%, according to research and consulting firm GlobalData.

West Introduces 1- to 3-mL NovaPure® Plunger for Higher Volume InjectionsWest Introduces 1- to 3-mL NovaPure® Plunger for Higher Volume Injections
West Pharmaceutical Services, Inc. recently announced the availability of the 1- to 3-mL NovaPure® plunger — an innovative, high-quality component for prefilled delivery systems, designed to reduce particulate, ensure consistency of delivery, and fit the changing needs of higher-volume injectable drug delivery systems

Gerresheimer Presents New COP Syringes Produced in Germany: Gx RTF ClearJect Gerresheimer Presents New COP Syringes Produced in Germany: Gx RTF ClearJect
On the occasion of this year's customer trade show, Gerresheimer Pharma Days held in Chicago, Illinois, the company presented the first product of its newly developed Gx RTF ClearJect brand: a COP syringe with cannula.

New Merger Between Pfizer & Anacor Set to Leverage Companies in Atopic Dermatitis SpaceNew Merger Between Pfizer & Anacor Set to Leverage Companies in Atopic Dermatitis Space
An upcoming merger agreement between Pfizer and Anacor, worth around $5.2 billion, could boost the marketing power of Anacor’s lead pipeline candidate, crisaborole, and pave the way for Pfizer to launch its own candidate, a topical form of Xeljanz, both for the treatment of mild-to-moderate atopic dermatitis, according to an analyst with research and consulting firm GlobalData.
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AAPS National Biotechnology Conference
May 16-18
Boston, MA

Cleaning Validation Summit
May 23-24, 2016
Racquet Club of Philadelphia, PA

BIO 2016
June 6-9
San Francisco, CA

PharmaPack
June 14-15
New York, NY

Controlled Release Society Meeting
July 17-20
Seattle, WA

Process Validation Summit
June 27-28, 2016
Racquet Club of Philadelphia, PA

Transdermal Drug Delivery Systems
September 12-13, 2016
Racquet Club of Philadelphia, PA

CPhI Worldwide
October 4-6
Barcelona, Spain

PDA – Universe of Pre-filled Syringes & Injection Devices
October 17-18
Huntington Beach, CA

Pharma Ed's Extractables and Leachables Forum
October 24-25, 2016
Racquet Club of Philadelphia

AAPS Annual Meeting
November 13-17
Denver, CO

 



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